MEDU-10. THERAPEUTIC TARGETING OF STEM CELL SELF-RENEWAL IN CHILDHOOD MEDULLOBLASTOMA: STRATEGIES FOR BLOCKING RECURRENCE

Medulloblastoma (MB) is the most common malignant pediatric brain tumor. Group 3 MB patients face the highest incidence of metastasis and poor overall survival. The early onset and aggressive nature of MB suggest a stem cell origin, where a highly self-renewing transformed cell of the postnatal cere...

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Dettagli Bibliografici
Pubblicato in:Neuro Oncol
Autori principali: Bakhshinyan, David, Kameda-Smith, Michelle, Adile, Ashley, Manoranjan, Branavan, Venugopal, Chitra, Singh, Sheila
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2019
Soggetti:
Medulloblastoma
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6477203/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noz036.169
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