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Nucleoside Hydrolase NH 36: A Vital Enzyme for the Leishmania Genus in the Development of T-Cell Epitope Cross-Protective Vaccines

NH36 is a vital enzyme of the DNA metabolism and a specific target for anti-Leishmania chemotherapy. We developed second-generation vaccines composed of the FML complex or its main native antigen, the NH36 nucleoside hydrolase of Leishmania (L.) donovani and saponin, and a DNA vaccine containing the...

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Библиографические подробности
Опубликовано в: :Front Immunol
Главный автор: Palatnik-de-Sousa, Clarisa Beatriz
Формат: Artigo
Язык:Inglês
Опубликовано: Frontiers Media S.A. 2019
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6477039/
https://ncbi.nlm.nih.gov/pubmed/31040850
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.00813
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