Design and synthesis of anticancer 1-hydroxynaphthalene-2-carboxanilides with a p53 independent mechanism of action

A series of 116 small-molecule 1-hydroxynaphthalene-2-carboxanilides was designed based on the fragment-based approach and was synthesized according to the microwave-assisted protocol. The biological activity of all of the compounds was tested on human colon carcinoma cell lines including a deleted...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Sci Rep
Egile Nagusiak: Spaczyńska, Ewelina, Mrozek-Wilczkiewicz, Anna, Malarz, Katarzyna, Kos, Jiri, Gonec, Tomas, Oravec, Michal, Gawecki, Robert, Bak, Andrzej, Dohanosova, Jana, Kapustikova, Iva, Liptaj, Tibor, Jampilek, Josef, Musiol, Robert
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group UK 2019
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6476888/
https://ncbi.nlm.nih.gov/pubmed/31011161
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-42595-y
Etiketak: Etiketa erantsi
Etiketarik gabe, Izan zaitez lehena erregistro honi etiketa jartzen!

Antzeko izenburuak