Clinical significance of intratumoral HER2 heterogeneity on trastuzumab efficacy using endoscopic biopsy specimens in patients with advanced HER2 positive gastric cancer

BACKGROUND: We recently reported the clinical significance of intratumoral HER2 heterogeneity on trastuzumab efficacy using surgical specimens; patients with homogeneously HER2 positive gastric cancer benefitted more from trastuzumab. However, the majority of patients are diagnosed by endoscopic bio...

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Detalhes bibliográficos
Publicado no:Gastric Cancer
Main Authors: Yagi, Shusuke, Wakatsuki, Takeru, Yamamoto, Noriko, Chin, Keisho, Takahari, Daisuke, Ogura, Mariko, Ichimura, Takashi, Nakayama, Izuma, Osumi, Hiroki, Shinozaki, Eiji, Suenaga, Mitsukuni, Fujisaki, Junko, Ishikawa, Yuichi, Yamaguchi, Kensei, Namikawa, Ken, Horiuchi, Yusuke
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Singapore 2018
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6476840/
https://ncbi.nlm.nih.gov/pubmed/30328533
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10120-018-0887-x
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