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Granulocyte Macrophage-Colony-stimulating Factor Autoantibodies and Increased Intestinal Permeability in Crohn Disease
BACKGROUND: Alterations in intestinal permeability have been implicated in the pathogenesis of Crohn disease (CD). We have reported that granulocyte macrophage-colony-stimulating factor (GM-csF) is required for mucosal barrier function in mice, and elevated neutralizing GM-CsF autoantibodies (Ab) ar...
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| 發表在: | J Pediatr Gastroenterol Nutr |
|---|---|
| Main Authors: | , , , , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2011
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6476427/ https://ncbi.nlm.nih.gov/pubmed/21502824 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/MPG.0b013e3181fe2d93 |
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