Blood-Brain Barrier Development: Systems Modeling and Predictive Toxicology

The blood-brain barrier (BBB) serves as a gateway for passage of drugs, chemicals, nutrients, metabolites and hormones between vascular and neural compartments in the brain. Here, we review BBB development with regard to the microphysiology of the neurovascular unit (NVU) and the impact of BBB disru...

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Bibliografske podrobnosti
izdano v:Birth Defects Res
Main Authors: Saili, Katerine S., Zurlinden, Todd J., Schwab, Andrew J., Silvin, Aymeric, Baker, Nancy C., Sidney Hunter, E., Ginhoux, Florent, Knudsen, Thomas B.
Format: Artigo
Jezik:Inglês
Izdano: 2017
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6476421/
https://ncbi.nlm.nih.gov/pubmed/29251840
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bdr2.1180
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