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Cu-Mediated Aminoquinoline-Directed Radiofluorination of Aromatic C–H Bonds with K(18)F
This communication describes a Cu-mediated ortho-C–H radiofluorination of aromatic carboxylic acids that are protected as 8-aminoquinoline benzamides. The method uses K(18)F and is compatible with a wide range of functional groups. The reaction is showcased in the high specific activity automated sy...
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| Published in: | Angew Chem Int Ed Engl |
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| Main Authors: | , , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
2019
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6476334/ https://ncbi.nlm.nih.gov/pubmed/30605563 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201812701 |
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