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Quantitating transcription factor redundancy: The relative roles of the ELT-2 and ELT-7 GATA factors in the C. elegans endoderm

The two GATA transcription factors ELT-2 and ELT-7 function in the differentiation of the C. elegans intestine. ELT-2 loss causes lethality. ELT-7 loss causes no obvious phenotype but enhances the elt-2(−) intestinal phenotype. Thus, ELT-2 and ELT-7 appear partially redundant, with ELT-2 being more...

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Publicat a:Dev Biol
Autors principals: Dineen, Aidan, Nishimura, Erin Osborne, Goszczynski, Barbara, Rothman, Joel H., McGhee, James D.
Format: Artigo
Idioma:Inglês
Publicat: 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6476323/
https://ncbi.nlm.nih.gov/pubmed/29360433
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2017.12.023
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