Engineering a Model Cell for Rational Tuning of GPCR Signaling

G protein-coupled receptor (GPCR) signaling is the primary method eukaryotes use to respond to specific cues in their environment. However, the relationship between stimulus and response for each GPCR is difficult to predict due to diversity in natural signal transduction architecture and expression...

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Publicat a:Cell
Autors principals: Shaw, William M., Yamauchi, Hitoshi, Mead, Jack, Gowers, Glen-Oliver F., Bell, David J., Öling, David, Larsson, Niklas, Wigglesworth, Mark, Ladds, Graham, Ellis, Tom
Format: Artigo
Idioma:Inglês
Publicat: Cell Press 2019
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6476273/
https://ncbi.nlm.nih.gov/pubmed/30955892
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2019.02.023
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