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β1-Adrenoreceptor Polymorphisms and Blood Pressure: 49S Variant Increases Plasma Renin But Not Blood Pressure in Hypertensive Patients

BACKGROUND: Activation of beta-1 adrenoreceptor (β1-AR) in the kidney releases renin that plays a major role in the maintenance of blood pressure. Genetic variation in β1-AR could therefore alter the physiological and clinical effects of this hormone. We tested this hypothesis in patients from a pri...

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Bibliographic Details
Published in:Am J Hypertens
Main Authors: Sandilands, Alastair J, O’Shaughnessy, Kevin M, , Yasmin
Format: Artigo
Language:Inglês
Published: Oxford University Press 2019
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6475877/
https://ncbi.nlm.nih.gov/pubmed/30753253
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ajh/hpz019
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