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Comparison of the Whole-Genome Sequence of an Oka Varicella Vaccine from China with Other Oka Vaccine Strains Reveals Sites Putatively Critical for Vaccine Efficacy

Varicella-zoster virus (VZV) infection results in varicella mostly in children. Reactivation of the virus causes herpes zoster (HZ), mostly in adults. A live attenuated vaccine (vOka-Biken) was originally derived from the parental strain pOka. Several live attenuated vaccines based on the Oka strain...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Wu, Qiuhua, Rivailler, Pierre, Xu, Songtao, Xu, Wenbo
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6475776/
https://ncbi.nlm.nih.gov/pubmed/30728261
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02281-18
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