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Fluorescence enhancement of a microbial rhodopsin via electronic reprogramming

The engineering of microbial rhodopsins with enhanced fluorescence is of great importance in the expanding field of optogenetics. Here we report the discovery of two mutants (W76S/Y179F and L83Q) of a sensory rhodopsin from the cyanobacterium Anabaena PCC7120 with opposite fluorescence behavior. In...

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Detalhes bibliográficos
Publicado no:J Am Chem Soc
Main Authors: del Carmen Marín, María, Agathangelou, Damianos, Orozco-Gonzalez, Yoelvis, Valentini, Alessio, Kato, Yoshitaka, Abe-Yoshizumi, Rei, Kandori, Hideki, Choi, Ahreum, Jung, Kwang-Hwan, Haacke, Stefan, Olivucci, Massimo
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6475468/
https://ncbi.nlm.nih.gov/pubmed/30532962
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.8b09311
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