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Papain-like cysteine proteases prepare plant cyclic peptide precursors for cyclization

Cyclotides are plant defense peptides that have been extensively investigated for pharmaceutical and agricultural applications, but key details of their posttranslational biosynthesis have remained elusive. Asparaginyl endopeptidases are crucial in the final stage of the head-to-tail cyclization rea...

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Bibliografische gegevens
Gepubliceerd in:Proc Natl Acad Sci U S A
Hoofdauteurs: Rehm, Fabian B. H., Jackson, Mark A., De Geyter, Ewout, Yap, Kuok, Gilding, Edward K., Durek, Thomas, Craik, David J.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: National Academy of Sciences 2019
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6475389/
https://ncbi.nlm.nih.gov/pubmed/30944220
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1901807116
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