Prolactin Receptor Signaling Regulates a Pregnancy-Specific Transcriptional Program in Mouse Islets

Pancreatic β-cells undergo profound hyperplasia during pregnancy to maintain maternal euglycemia. Failure to reprogram β-cells into a more replicative state has been found to underlie susceptibility to gestational diabetes mellitus (GDM). We recently identified a requirement for prolactin receptor (...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Endocrinology
Prif Awduron: Pepin, Mark E, Bickerton, Hayden H, Bethea, Maigen, Hunter, Chad S, Wende, Adam R, Banerjee, Ronadip R
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Endocrine Society 2019
Pynciau:
Research Articles
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6475113/
https://ncbi.nlm.nih.gov/pubmed/31004482
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2018-00991
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