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The KCl cotransporter isoform KCC3 can play an important role in cell growth regulation

The KCl cotransporter (KCC) plays a significant role in the ionic and osmotic homeostasis of many cell types. Four KCC isoforms have been cloned. KCC1 and KCC4 activity is osmolality-sensitive and involved in volume regulation. KCC2, a neuronal-specific isoform, can lower intracellular Cl(−) and is...

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Main Authors: Shen, Meng-Ru, Chou, Cheng-Yang, Hsu, Keng-Fu, Liu, Hsiao-Sheng, Dunham, Philip B., Holtzman, Eli J., Ellory, J. Clive
Formato: Artigo
Idioma:Inglês
Publicado: The National Academy of Sciences 2001
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC64747/
https://ncbi.nlm.nih.gov/pubmed/11724933
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.251388798
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