Thioglycosides are efficient metabolic decoys of glycosylation that reduce selectin dependent leukocyte adhesion

Metabolic decoys are synthetic analogs of naturally occurring biosynthetic acceptors. These compounds divert cellular biosynthetic pathways by acting as artificial substrates that usurp the activity of natural enzymes. While O-linked glycosides are common, they are only partially effective even at m...

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Detalhes bibliográficos
Publicado no:Cell Chem Biol
Main Authors: Wang, Shuen-Shiuan, Gao, Xuefeng, del Solar, Virginia, Yu, Xinheng, Antonopoulos, Aristotelis, Friedman, Alan E., Matich, Eryn K., Atilla-Gokcumen, G. Ekin, Nasirikenari, Mehrab, Lau, Joseph T., Dell, Anne, Haslam, Stuart M., Laine, Roger A., Matta, Khushi L., Neelamegham, Sriram
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6474417/
https://ncbi.nlm.nih.gov/pubmed/30344053
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chembiol.2018.09.012
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