Effect of Estradiol in an Azoxymethane/Dextran Sulfate Sodium-Treated Mouse Model of Colorectal Cancer: Implication for Sex Difference in Colorectal Cancer Development

PURPOSE: This study demonstrates that estradiol downregulates inflammation and inhibits colorectal cancer (CRC) development in azoxymethane/dextran sulfate sodium (AOM/DSS) mouse model. MATERIALS AND METHODS: AOM/DSS-treated male and female mice were sacrificed at weeks 2, 10, and 16, to assess estr...

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Vydáno v:Cancer Res Treat
Hlavní autoři: Son, Hee Jin, Sohn, Sung Hwa, Kim, Nayoung, Lee, Ha-Na, Lee, Sun Min, Nam, Ryoung Hee, Park, Ji Hyun, Song, Chin-Hee, Shin, Eun, Na, Hee Young, Kim, Joo Sung, Lee, Dong Ho, Surh, Young-Joon
Médium: Artigo
Jazyk:Inglês
Vydáno: Korean Cancer Association 2019
Témata:
Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6473282/
https://ncbi.nlm.nih.gov/pubmed/30064198
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4143/crt.2018.060
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