Extension of Maximal Lifespan and High Bone Marrow Chimerism After Nonmyeloablative Syngeneic Transplantation of Bone Marrow From Young to Old Mice

The goal of this work was to determine the effect of nonablative syngeneic transplantation of young bone marrow (BM) to laboratory animals (mice) of advanced age upon maximum duration of their lifespan. To do this, transplantation of 100 million nucleated cells from BM of young syngeneic donors to a...

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Veröffentlicht in:Front Genet
Hauptverfasser: Kovina, Marina V., Karnaukhov, Alexey V., Krasheninnikov, Mikhail E., Kovin, Artem L., Gazheev, Sarul T., Sergievich, Larisa A., Karnaukhova, Elena V., Bogdanenko, Elena V., Balyasin, Maxim V., Khodarovich, Yury M., Dyuzheva, Tatyana G., Lyundup, Alexey V.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2019
Schlagworte:
Genetics
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6473025/
https://ncbi.nlm.nih.gov/pubmed/31031800
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2019.00310
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