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A quorum sensing-associated virulence gene of Pseudomonas aeruginosa encodes a LysR-like transcription regulator with a unique self-regulatory mechanism

The human opportunistic pathogen Pseudomonas aeruginosa strain PA14 infects both plants and animals. Previously, using plants to screen directly for P. aeruginosa virulence-attenuated mutants, we identified a locus, pho34B12, relevant in mammalian pathogenesis. Here, nonsense point mutations in the...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Cao, Hui, Krishnan, Gomathi, Goumnerov, Boyan, Tsongalis, John, Tompkins, Ronald, Rahme, Laurence G.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2001
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC64730/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11724939/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.251465298
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