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A quorum sensing-associated virulence gene of Pseudomonas aeruginosa encodes a LysR-like transcription regulator with a unique self-regulatory mechanism

The human opportunistic pathogen Pseudomonas aeruginosa strain PA14 infects both plants and animals. Previously, using plants to screen directly for P. aeruginosa virulence-attenuated mutants, we identified a locus, pho34B12, relevant in mammalian pathogenesis. Here, nonsense point mutations in the...

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Hlavní autoři: Cao, Hui, Krishnan, Gomathi, Goumnerov, Boyan, Tsongalis, John, Tompkins, Ronald, Rahme, Laurence G.
Médium: Artigo
Jazyk:Inglês
Vydáno: The National Academy of Sciences 2001
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC64730/
https://ncbi.nlm.nih.gov/pubmed/11724939
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.251465298
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