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Qa-1-Restricted CD8(+) T Cells Can Compensate for the Absence of Conventional T Cells during Viral Infection

The role of non-classical T cells during viral infection remains poorly understood. Using the well-established murine model of CMV infection (MCMV) and mice deficient in MHC class Ia molecules, we found that non-classical CD8(+) T cells robustly expand after MCMV challenge, become highly activated e...

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Detalhes bibliográficos
Publicado no:Cell Rep
Main Authors: Anderson, Courtney K., Reilly, Emma C., Lee, Angus Y., Brossay, Laurent
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6472915/
https://ncbi.nlm.nih.gov/pubmed/30970256
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2019.03.059
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