TGFβ-activation by dendritic cells drives Th17 induction and intestinal contractility and augments the expulsion of the parasite Trichinella spiralis in mice

Helminths are highly prevalent metazoan parasites that infect over a billion of the world’s population. Hosts have evolved numerous mechanisms to drive the expulsion of these parasites via Th2-driven immunity, but these responses must be tightly controlled to prevent equally devastating immunopathol...

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Pubblicato in:PLoS Pathog
Autori principali: Steel, Nicola, Faniyi, Aduragbemi A., Rahman, Sayema, Swietlik, Stefanie, Czajkowska, Beata I., Chan, Bethany T., Hardgrave, Alexander, Steel, Anthony, Sparwasser, Tim D., Assas, Mushref B., Grencis, Richard K., Travis, Mark A., Worthington, John J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2019
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6472816/
https://ncbi.nlm.nih.gov/pubmed/30998782
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1007657
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