Baicalein inhibits fibronectin-induced epithelial–mesenchymal transition by decreasing activation and upregulation of calpain-2

The extracellular matrix protein fibronectin (FN) facilitates tumorigenesis and the development of breast cancer. Inhibition of the FN-induced cellular response is a potential strategy for breast cancer treatment. In the present study, we investigated the effects of the flavonoid baicalein on FN-ind...

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Vydáno v:Cell Death Dis
Hlavní autoři: Chen, Yan, Chen, Lin, Hong, Duanyang, Chen, Zongyue, Zhang, Jingyu, Fu, Lingyun, Pan, Di, Zhang, Yanyan, Xu, Yini, Gan, Shiquan, Xiao, Chaoda, Tao, Ling, Shen, Xiangchun
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2019
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6472504/
https://ncbi.nlm.nih.gov/pubmed/31000696
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-019-1572-7
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