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Cell-penetrating peptide sequence and modification dependent uptake and subcellular distribution of green florescent protein in different cell lines

Protein therapy holds great promise for treating a variety of diseases. To act on intracellular targets, therapeutic proteins must cross the plasma membrane. This has previously been achieved by covalent attachment to a variety of cell-penetrating peptides (CPPs). However, there is limited informati...

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Bibliografiska uppgifter
I publikationen:Sci Rep
Huvudupphovsmän: Patel, Sanjay G., Sayers, Edward J., He, Lin, Narayan, Rohan, Williams, Thomas L., Mills, Emily M., Allemann, Rudolf K., Luk, Louis Y. P., Jones, Arwyn T., Tsai, Yu-Hsuan
Materialtyp: Artigo
Språk:Inglês
Publicerad: Nature Publishing Group UK 2019
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6472342/
https://ncbi.nlm.nih.gov/pubmed/31000738
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-42456-8
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