Influence of high glucose on mesangial cell-derived exosome composition, secretion and cell communication

Mesangial cells stimulated with high glucose (HG) exhibit increased intracellular angiotensin II (AngII) synthesis that is correlated with the upregulation of AngII target genes, such as profibrotic cytokines. The intracrine effects of AngII can be mediated by several molecules transferred to other...

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Bibliografiske detaljer
Udgivet i:Sci Rep
Main Authors: da Silva Novaes, Antônio, Borges, Fernanda Teixeira, Maquigussa, Edgar, Varela, Vanessa Araújo, Dias, Marcos Vinicios Salles, Boim, Mirian Aparecida
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6472340/
https://ncbi.nlm.nih.gov/pubmed/31000742
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-42746-1
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