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IL-15 plays a major role in the persistence of Tax-specific CD8 cells in HAM/TSP patients

IL-15 is a critical cytokine for the maintenance of memory-phenotype CD8 cells in mice. Here, we investigated the role of IL-15 in the neurological disease termed human T cell lymphotropic virus I-associated myelopathy/tropical spastic paraparesis (HAM/TSP). The high number of viral-specific CD8 cel...

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Detalhes bibliográficos
Main Authors: Azimi, Nazli, Nagai, Masahiro, Jacobson, Steven, Waldmann, Thomas A.
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC64721/
https://ncbi.nlm.nih.gov/pubmed/11717409
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.251540598
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