Steroids from the Deep-Sea-Derived Fungus Penicillium granulatum MCCC 3A00475 Induced Apoptosis via Retinoid X Receptor (RXR)-α Pathway

Five new ergostanes, penicisteroids D−H (1−5), were isolated from the liquid culture of the deep-sea-derived fungus Penicillium granulatum MCCC 3A00475, along with 27 known compounds. The structures of the new steroids were established mainly on the basis of extensive analysis of 1D and 2D NMR as we...

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Vydáno v:Mar Drugs
Hlavní autoři: Xie, Chun-Lan, Zhang, Duo, Xia, Jin-Mei, Hu, Chao-Chao, Lin, Ting, Lin, Yu-Kun, Wang, Guang-Hui, Tian, Wen-Jing, Li, Zeng-Peng, Zhang, Xiao-Kun, Yang, Xian-Wen, Chen, Hai-Feng
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2019
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6472029/
https://ncbi.nlm.nih.gov/pubmed/30893778
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/md17030178
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