Loss of sphingosine 1-phosphate (S1P) in septic shock is predominantly caused by decreased levels of high-density lipoproteins (HDL)

BACKGROUND: Sphingosine 1-phosphate (S1P) is a signaling lipid essential in regulating processes involved in sepsis pathophysiology, including endothelial permeability and vascular tone. Serum S1P is progressively reduced in sepsis patients with increasing severity. S1P function depends on binding t...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:J Intensive Care
Egile Nagusiak: Winkler, Martin Sebastian, Märtz, Konstantin B., Nierhaus, Axel, Daum, Günter, Schwedhelm, Edzard, Kluge, Stefan, Gräler, Markus H.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: BioMed Central 2019
Gaiak:
Research
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6472014/
https://ncbi.nlm.nih.gov/pubmed/31019718
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40560-019-0376-2
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