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Effect of A22 on the Conformation of Bacterial Actin MreB

The mechanism of the antibiotic molecule A22 is yet to be clearly understood. In a previous study, we carried out molecular dynamics simulations of a monomer of the bacterial actin-like MreB in complex with different nucleotides and A22, and suggested that A22 impedes the release of P(i) from the ac...

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Détails bibliographiques
Publié dans:Int J Mol Sci
Auteurs principaux: Awuni, Elvis, Mu, Yuguang
Format: Artigo
Langue:Inglês
Publié: MDPI 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6471442/
https://ncbi.nlm.nih.gov/pubmed/30875875
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20061304
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