Sulfide (Na(2)S) and Polysulfide (Na(2)S(2)) Interacting with Doxycycline Produce/Scavenge Superoxide and Hydroxyl Radicals and Induce/Inhibit DNA Cleavage

Doxycycline (DOXY) is an antibiotic routinely prescribed in human and veterinary medicine for antibacterial treatment, but it has also numerous side effects that include oxidative stress, inflammation, cancer or hypoxia-induced injury. Endogenously produced hydrogen sulfide (H(2)S) and polysulfides...

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Publicado no:Molecules
Main Authors: Misak, Anton, Kurakova, Lucia, Goffa, Eduard, Brezova, Vlasta, Grman, Marian, Ondriasova, Elena, Chovanec, Miroslav, Ondrias, Karol
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6470963/
https://ncbi.nlm.nih.gov/pubmed/30909480
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules24061148
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