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Sulfide (Na(2)S) and Polysulfide (Na(2)S(2)) Interacting with Doxycycline Produce/Scavenge Superoxide and Hydroxyl Radicals and Induce/Inhibit DNA Cleavage

Doxycycline (DOXY) is an antibiotic routinely prescribed in human and veterinary medicine for antibacterial treatment, but it has also numerous side effects that include oxidative stress, inflammation, cancer or hypoxia-induced injury. Endogenously produced hydrogen sulfide (H(2)S) and polysulfides...

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Bibliografske podrobnosti
izdano v:	Molecules
Main Authors:	Misak, Anton, Kurakova, Lucia, Goffa, Eduard, Brezova, Vlasta, Grman, Marian, Ondriasova, Elena, Chovanec, Miroslav, Ondrias, Karol
Format:	Artigo
Jezik:	Inglês
Izdano:	MDPI 2019
Teme:	Article
Online dostop:	https://ncbi.nlm.nih.gov/pmc/articles/PMC6470963/ https://ncbi.nlm.nih.gov/pubmed/30909480 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules24061148
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Sulfide (Na(2)S) and Polysulfide (Na(2)S(2)) Interacting with Doxycycline Produce/Scavenge Superoxide and Hydroxyl Radicals and Induce/Inhibit DNA Cleavage

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