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Effects of Verapamil and Diltiazem on the Pharmacokinetics and Pharmacodynamics of Rivaroxaban

Concomitant use of rivaroxaban with non-dihydropyridine calcium channel blockers (non-DHPs) might lead to an increase of systemic rivaroxaban exposure and anticoagulant effects in relation to the inhibition of metabolic enzymes and/or transporters by non-DHPs. This study was designed to evaluate the...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Pharmaceutics
Hauptverfasser: Kim, Minsoo, Son, Heebin, Noh, Keumhan, Kim, Eunyoung, Shin, Beom Soo, Kang, Wonku
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6470838/
https://ncbi.nlm.nih.gov/pubmed/30893910
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pharmaceutics11030133
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