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Protective Effect of N-Arachidonoyl Glycine-GPR18 Signaling after Excitotoxical Lesion in Murine Organotypic Hippocampal Slice Cultures

N-arachidonoyl glycine (NAGly) is an endocannabinoid involved in the regulation of different immune cells. It was shown to activate the GPR18 receptor, which was postulated to switch macrophages from cytotoxic to reparative. To study GPR18 expression and neuroprotection after NAGly treatment we used...

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Vydáno v:Int J Mol Sci
Hlavní autoři: Grabiec, Urszula, Hohmann, Tim, Ghadban, Chalid, Rothgänger, Candy, Wong, Daniel, Antonietti, Alexandra, Groth, Thomas, Mackie, Ken, Dehghani, Faramarz
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2019
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6470786/
https://ncbi.nlm.nih.gov/pubmed/30871175
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20061266
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