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Toll-Like Receptor-Mediated Recognition of Nucleic Acid Nanoparticles (NANPs) in Human Primary Blood Cells

Infusion reactions (IRs) create a translational hurdle for many novel therapeutics, including those utilizing nanotechnology. Nucleic acid nanoparticles (NANPs) are a novel class of therapeutics prepared by rational design of relatively short oligonucleotides to self-assemble into various programmab...

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Hong, Enping, Halman, Justin R., Shah, Ankit, Cedrone, Edward, Truong, Nguyen, Afonin, Kirill A., Dobrovolskaia, Marina A.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6470694/
https://ncbi.nlm.nih.gov/pubmed/30897721
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules24061094
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