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Structure–Function and Therapeutic Potential of Spider Venom-Derived Cysteine Knot Peptides Targeting Sodium Channels
Spider venom-derived cysteine knot peptides are a mega-diverse class of molecules that exhibit unique pharmacological properties to modulate key membrane protein targets. Voltage-gated sodium channels (Na(V)) are often targeted by these peptides to allosterically promote opening or closing of the ch...
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| Publicado no: | Front Pharmacol |
|---|---|
| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Frontiers Media S.A.
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6470632/ https://ncbi.nlm.nih.gov/pubmed/31031623 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2019.00366 |
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