Ageing in Pgc-1β(−/−) mice modelling mitochondrial dysfunction induces differential expression of a range of genes regulating ventricular electrophysiology

Mice deficient in mitochondrial promoter peroxisome proliferator activated receptor-γ co-activator-1β (Pgc-1β(−/−)) is a valuable model for metabolic diseases and has been found to present with several pathologies including ventricular arrhythmia. In the present study, our aim was to shed light on t...

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Dettagli Bibliografici
Pubblicato in:Biosci Rep
Autori principali: Edling, Charlotte E., Fazmin, Ibrahim T., Chadda, Karan R., Ahmad, Shiraz, Valli, Haseeb, Grace, Andrew A., Huang, Christopher L.-H., Jeevaratnam, Kamalan
Natura: Artigo
Lingua:Inglês
Pubblicazione: Portland Press Ltd. 2019
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Research Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6470410/
https://ncbi.nlm.nih.gov/pubmed/30914453
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BSR20190127
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