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Application of triple quadrupole mass spectrometry for the characterization of antibody–drug conjugates

Antibody–drug conjugates (ADCs) are an inherently heterogeneous class of biotherapeutics, the development of which requires extensive characterization throughout. During the earliest phases of preclinical development, when synthetic routes towards the desired conjugate are being assessed, the main i...

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Detalhes bibliográficos
Publicado no:Anal Bioanal Chem
Main Authors: Källsten, Malin, Pijnappel, Matthijs, Hartmann, Rafael, Lehmann, Fredrik, Kovac, Lucia, Lind, Sara Bergström, Bergquist, Jonas
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Berlin Heidelberg 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6470114/
https://ncbi.nlm.nih.gov/pubmed/30848315
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00216-019-01699-0
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