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Fibroblast growth factor-2 binding to heparan sulfate proteoglycans varies with shear stress in flow-adapted cells.

Fibroblast Growth Factor 2 (FGF2), an important regulator of angiogenesis, binds to endothelial cell (EC) surface fibroblast growth factor receptors (FGFR) and heparan sulfate proteoglycans (HSPG). FGF2 binding kinetics have been predominantly studied in static culture; however, the endothelium is c...

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Bibliografski detalji
Izdano u:Ann Biomed Eng
Glavni autori: Garcia, Jonathan, Patel, Nisha, Basehore, Sarah, Clyne, Alisa Morss
Format: Artigo
Jezik:Inglês
Izdano: 2019
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6470077/
https://ncbi.nlm.nih.gov/pubmed/30689065
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10439-019-02202-7
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