Discovery of glycerol phosphate modification on streptococcal rhamnose polysaccharides

Cell wall glycopolymers on the surface of Gram-positive bacteria are fundamental to bacterial physiology and infection biology. Here we identify gacH, a gene in the S. pyogenes Group A Carbohydrate (GAC) biosynthetic cluster, in two independent transposon library screens for its ability to confer re...

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Publicado en:Nat Chem Biol
Main Authors: Edgar, Rebecca J., van Hensbergen, Vincent P., Ruda, Alessandro, Turner, Andrew G., Deng, Pan, Breton, Yoann Le, El-Sayed, Najib M., Belew, Ashton T., McIver, Kevin S., McEwan, Alastair G., Morris, Andrew J., Lambeau, Gérard, Walker, Mark J., Rush, Jeffrey S., Korotkov, Konstantin V., Widmalm, Göran, van Sorge, Nina M., Korotkova, Natalia
Formato: Artigo
Idioma:Inglês
Publicado: 2019
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6470023/
https://ncbi.nlm.nih.gov/pubmed/30936502
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41589-019-0251-4
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