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Functional characterization of AC5 gain-of-function variants: Impact on the molecular basis of ADCY5-related dyskinesia
Adenylyl cyclases are key points for the integration of stimulatory and inhibitory G protein-coupled receptor (GPCR) signals. Adenylyl cyclase type 5 (AC5) is highly expressed in striatal medium spiny neurons (MSNs), and is known to play an important role in mediating striatal dopaminergic signaling...
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| Publicado en: | Biochem Pharmacol |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2019
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6470011/ https://ncbi.nlm.nih.gov/pubmed/30772269 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcp.2019.02.005 |
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