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Why does RNA collapse? The importance of water in a simulation study of helix-junction-helix systems

Using computer simulations we consider the balance of thermodynamic forces that collapse RNA. A model helix-junction-helix (HJH) construct is used to investigate the transition from an extended to a collapsed conformation. Conventional Molecular Dynamics and Milestoning simulations are used to study...

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Bibliografische gegevens
Gepubliceerd in:J Am Chem Soc
Hoofdauteurs: Templeton, Clark, Elber, Ron
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2018
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6470002/
https://ncbi.nlm.nih.gov/pubmed/30465606
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.8b11111
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