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Spinocerebellar ataxias: prospects and challenges for therapy development

The spinocerebellar ataxias (SCAs) comprise more than 40 autosomal dominant neurodegenerative disorders that present principally with progressive ataxia. Within the past few years, studies of pathogenic mechanisms in the SCAs have led to the development of promising therapeutic strategies, especiall...

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Bibliographic Details
Published in:Nat Rev Neurol
Main Authors: Ashizawa, Tetsuo, Öz, Gülin, Paulson, Henry L.
Format: Artigo
Language:Inglês
Published: 2018
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6469934/
https://ncbi.nlm.nih.gov/pubmed/30131520
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41582-018-0051-6
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