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CRISPR/Cas precision: do we need to worry about off-targeting in plants?

The CRISPR/Cas technology has recently become the tool of choice for targeted genome modification in plants and beyond. Although CRSIPR/Cas offers a rapid and facile way of introducing changes at genomic loci of interest, its application is associated with off-targeting, i.e. introduction of uninten...

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Detalhes bibliográficos
Publicado no:Plant Cell Rep
Main Authors: Hahn, Florian, Nekrasov, Vladimir
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Berlin Heidelberg 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6469637/
https://ncbi.nlm.nih.gov/pubmed/30426198
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00299-018-2355-9
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