AIBP-mediated Cholesterol Efflux Instructs Hematopoietic Stem and Progenitor Cell Fate

Hypercholesterolemia, the driving force of atherosclerosis, accelerates the expansion and mobilization of hematopoietic stem and progenitor cells (HSPCs). The molecular determinants connecting hypercholesterolemia with hematopoiesis are unclear. Here we report that a somite-derived pro-hematopoietic...

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Опубликовано в: :Science
Главные авторы: Gu, Qilin, Yang, Xiaojie, Lv, Jie, Zhang, Jiaxiong, Xia, Bo, Kim, Jun-dae, Wang, Ruoyu, Xiong, Feng, Meng, Shu, Clements, Thomas P., Tandon, Bhavna, Wagner, Daniel S., Diaz, Miguel F., Wenzel, Pamela L., Miller, Yury I., Traver, David, Cooke, John P., Li, Wenbo, Zon, Leonard I., Chen, Kaifu, Bai, Yongping, Fang, Longhou
Формат: Artigo
Язык:Inglês
Опубликовано: 2019
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6469354/
https://ncbi.nlm.nih.gov/pubmed/30705153
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aav1749
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