Učitavanje...
Nonsynonymous, synonymous and nonsense mutations in human cancer-related genes undergo stronger purifying selections than expectation
BACKGROUND: Nonsynonymous mutations change the protein sequences and are frequently subjected to natural selection. The same goes for nonsense mutations that introduce pre-mature stop codons into CDSs (coding sequences). Synonymous mutations, however, are intuitively thought to be functionally silen...
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| Izdano u: | BMC Cancer |
|---|---|
| Glavni autori: | , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
BioMed Central
2019
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6469204/ https://ncbi.nlm.nih.gov/pubmed/30991970 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-019-5572-x |
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