[(177)Lu]Lu-PSMA-617 Salivary Gland Uptake Characterized by Quantitative In Vitro Autoradiography

Irradiation of salivary glands remains the main dose-limiting side effect of therapeutic PSMA-inhibitors, especially when using alpha emitters. Thus, further advances in radiopharmaceutical design and therapy strategies are needed to reduce salivary gland uptake, thereby allowing the administration...

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Bibliographic Details
Published in:Pharmaceuticals (Basel)
Main Authors: Tönnesmann, Roswitha, Meyer, Philipp T., Eder, Matthias, Baranski, Ann-Christin
Format: Artigo
Language:Inglês
Published: MDPI 2019
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6469177/
https://ncbi.nlm.nih.gov/pubmed/30678341
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ph12010018
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