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Development of a Microwave-assisted Chemoselective Synthesis of Oxime-linked Sugar Linkers and Trivalent Glycoclusters

A rapid, high-yielding microwave-mediated synthetic procedure was developed and optimized using a model system of monovalent sugar linkers, with the ultimate goal of using this method for the synthesis of multivalent glycoclusters. The reaction occurs between the aldehyde/ketone on the sugars and an...

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Detalhes bibliográficos
Publicado no:Pharmaceuticals (Basel)
Main Authors: McReynolds, Katherine, Dimas, Dustin, Floyd, Grace, Zeman, Kara
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6469176/
https://ncbi.nlm.nih.gov/pubmed/30875805
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ph12010039
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