Ex vivo Dynamics of Human Glioblastoma Cells in a Microvasculature‐on‐a‐Chip System Correlates with Tumor Heterogeneity and Subtypes

The perivascular niche (PVN) plays an essential role in brain tumor stem‐like cell (BTSC) fate control, tumor invasion, and therapeutic resistance. Here, a microvasculature‐on‐a‐chip system as a PVN model is used to evaluate the ex vivo dynamics of BTSCs from ten glioblastoma patients. BTSCs are fou...

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Enregistré dans:
Détails bibliographiques
Publié dans:Adv Sci (Weinh)
Auteurs principaux: Xiao, Yang, Kim, Dongjoo, Dura, Burak, Zhang, Kerou, Yan, Runchen, Li, Huamin, Han, Edward, Ip, Joshua, Zou, Pan, Liu, Jun, Chen, Ann Tai, Vortmeyer, Alexander O., Zhou, Jiangbing, Fan, Rong
Format: Artigo
Langue:Inglês
Publié: John Wiley and Sons Inc. 2019
Sujets:
Full Papers
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6468969/
https://ncbi.nlm.nih.gov/pubmed/31016107
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/advs.201801531
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