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The Protein Tyrosine Phosphatase H1 PTPH1 Supports Proliferation of Keratinocytes and is a Target of the Human Papillomavirus Type 8 E6 Oncogene

Human papillomaviruses (HPV) replicate their DNA in the suprabasal layer of the infected mucosa or skin. In order to create a suitable environment for vegetative viral DNA replication HPV delay differentiation and sustain keratinocyte proliferation that can lead to hyperplasia. The mechanism underly...

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Bibliographic Details
Published in:Cells
Main Authors: Taute, Stefanie, Böhnke, Philipp, Sprissler, Jasmin, Buchholz, Stephanie, Hufbauer, Martin, Akgül, Baki, Steger, Gertrud
Format: Artigo
Language:Inglês
Published: MDPI 2019
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6468676/
https://ncbi.nlm.nih.gov/pubmed/30875834
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells8030244
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