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Lactate Activates the E2F Pathway to Promote Cell Motility by Up-Regulating Microtubule Modulating Genes

Excess lactate production due to enhanced aerobic glycolysis is characteristic of malignant cancers, which is also intimately associated with poor cancer prognoses. Although tumor-associated lactate contributes to all major steps in carcinogenesis, its action mechanism remains obscure. To understand...

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Detalhes bibliográficos
Publicado no:Cancers (Basel)
Main Authors: Jung, Yi-deun, Cho, Jung Hee, Park, Seulki, Kang, Minho, Park, Seung-jin, Choi, Dong Hee, Jeong, Moonkyung, Park, Kyung Chan, Yeom, Young Il, Lee, Dong Chul
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6468617/
https://ncbi.nlm.nih.gov/pubmed/30813560
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers11030274
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