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The Deubiquitylase USP4 Interacts with the Water Channel AQP2 to Modulate Its Apical Membrane Accumulation and Cellular Abundance

Aquaporin 2 (AQP2) mediates the osmotic water permeability of the kidney collecting duct in response to arginine vasopressin (VP) and is essential for body water homeostasis. VP effects on AQP2 occur via long-term alterations in AQP2 abundance and short-term changes in AQP2 localization. Several of...

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Pubblicato in:Cells
Autori principali: Murali, Sathish K., Aroankins, Takwa S., Moeller, Hanne B., Fenton, Robert A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6468601/
https://ncbi.nlm.nih.gov/pubmed/30901874
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells8030265
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