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Analysis of the Zn-Binding Domains of TRIM32, the E3 Ubiquitin Ligase Mutated in Limb Girdle Muscular Dystrophy 2H

Members of the tripartite motif family of E3 ubiquitin ligases are characterized by the presence of a conserved N-terminal module composed of a RING domain followed by one or two B-box domains, a coiled-coil and a variable C-terminal region. The RING and B-box are both Zn-binding domains but, while...

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Publicado en:Cells
Main Authors: Lazzari, Elisa, El-Halawany, Medhat S., De March, Matteo, Valentino, Floriana, Cantatore, Francesco, Migliore, Chiara, Onesti, Silvia, Meroni, Germana
Formato: Artigo
Idioma:Inglês
Publicado: MDPI 2019
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6468550/
https://ncbi.nlm.nih.gov/pubmed/30884854
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells8030254
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